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InVivoSIM anti-human IL-1β(Gevokizumab Biosimilar) clone:Gevokizumab
中文名稱:InVivoSIM 抗人 IL-1β(Gevokizumab 生物仿制藥)抗體,克?。篏evokizumab(目錄號#SIM0049)
Key features:
▲ Gevokizumab is a humanized antibody that reacts with human IL-1β. IL-1β is a potent proinflammatory cytokine produced primarily by monocytes.
▲ IL-1β is also involved in cell proliferation, apoptosis, immune cell activation, etc.
▲ The gevokizumab antibody binds a unique IL-1β epitope and reduces the binding of IL-1 to its receptor
(IL-1RI or CD121a).
▲ Gevokizumab is used in research involving diabetes, inflammation, rheumatoid arthritis,cardiovascular biology, and cancer immunotherapy.
Application: in vivo neutralization of human IL1β, in vitro neutralization of human IL1β, ELISA, Western blot, Flow
cytometry Research Area: Apoptosis, Cancer Biology, Immunology
Related targets: IFNγ, IL-1RI or CD121a, IL-1α, IL-4, IL-2
主要特點:
▲ Gevokizumab 是一種與人 IL-1β 反應的人源化抗體。IL-1β 是一種強效的促炎性細胞因子,主要由單核細胞產(chǎn)生。
▲ IL-1β 還參與細胞增殖、凋亡、免疫細胞激活等生物過程。
▲ Gevokizumab 抗體結(jié)合獨-特的 IL1β 表位,減少 IL-1 與其受體(IL1RI 或 CD121a)的結(jié)合。
▲ Gevokizumab 用于糖尿病、炎癥、類風濕性關(guān)節(jié)炎、心血管生物學和癌癥免疫療法的研究。
應用:體內(nèi)中和人 IL-1β,體外中和人 IL-1β,ELISA,Western blot,流式細胞術(shù)
研究領(lǐng)域:細胞凋亡、癌癥生物學、免疫學
相關(guān)靶點:IFNγ、IL-1RI 或 CD121a、IL-1α、IL-4、IL-2
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