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多不飽和脂肪酸(PUFAs)是重要的營(yíng)養(yǎng)物質(zhì)，當(dāng)飲食中不存在足夠的量時(shí)，會(huì)表現(xiàn)出明顯的缺乏綜合征。實(shí)際上所有細(xì)胞中的花生四烯酸都被酯化成膜磷脂，其存在通過多個(gè)相互連接的途徑受到嚴(yán)格的調(diào)節(jié)。游離花生四烯酸是類花生酸第二信使生物合成的瞬時(shí)關(guān)鍵底物。受體刺激的游離花生四烯酸的釋放、代謝和再攝取都是細(xì)胞信號(hào)和炎癥的重要方面。

嘌呤霉素是一種氨基核苷抗生素，來源于S. alboniger，通過導(dǎo)致新生多肽鏈過早終止來阻斷原核生物和真核生物中的蛋白質(zhì)合成。嘌呤霉素分子的一部分類似于氨酰化tRNA的3’末端。它進(jìn)入核糖體的A位點(diǎn)，并在肽基轉(zhuǎn)移酶中心附著于生長(zhǎng)中的多肽鏈。導(dǎo)致嘌呤酰化新生鏈的形成和過早的鏈釋放。3’位置含有一個(gè)酰胺鍵，而不是tRNA的正常酯鍵，使其更能抵抗水解并停止核糖體的活性。

Antipain . dihydrochloride抑制劑由Adipogen公司生產(chǎn)，該產(chǎn)品貨號(hào)為AG-CP3-7002-M025，規(guī)格是25 mg。如需購(gòu)買該產(chǎn)品，請(qǐng)聯(lián)系代理商欣博盛生物。

Ganglioside GD1b . disodium salt (bovine brain)化合物由Adipogen公司所生產(chǎn)，該款產(chǎn)品貨號(hào)是AG-CN2-9004-M001，規(guī)格為1 mg。如需購(gòu)買該產(chǎn)品，請(qǐng)聯(lián)系我們欣博盛生物。

CleanTag® Small RNA Library Prep Kit is compatible with Illumina® and Ion Torrent™ technology and contains all necessary components for small RNA library preparation for next-generation sequencing. T…

Ganglioside GQ1b . tetrasodium salt (bovine brain) Specifically promotes neural differentiation of human neuroblastoma cells.

A lipid-soluble neurotoxin that acts as a sodium channel modulator. Binds with high affinity to the open state of the voltage-sensitive sodium channels at site 2, thereby causing a persistent ……

Y-27632 is a highly potent, cell permeable, selective and ATP competitive inhibitor of ROCK1 and ROCK2 (IC50=800nM). It acts as a potent inhibitor of agonist-induced Ca2+sensitization of myosin ……

Sphingosine-1-phosphate (1-SPP) is a putative second messenger that mobilizes calcium from intracellular stores via an IP3 independent pathway, activation of phospholipase D and stimulation of ……

JC-1 is a very sensitive fluorescent probe to test Pgp activity. In acute myeloid leukemia (AML) samples JC-1 is capable of distinguishing between resistant, intermediate and sensitive groups……